Nuclear Envelope Function

The cell’s nuclear envelope also called as nuclear membrane, perinuclear envelope, karyotheca or nucleolemma; is a double lipid bilayer that encloses the genetic material in eukaryotic cells. The nuclear envelope function is to serve as a physical barrier by separating from the cytoplasm the contents of the nucleus, which in particular is DNA.

Several nuclear pores are found in the nuclear envelope, as these regulate and facilitate the exchange of materials (such as RNA and protein transcription factors) between the cytoplasm and the nucleus. Each of the two membranes is composed of a lipid bilayer. Wherein the outer membrane is in joint with the rough endoplasmic reticulum and the inner nuclear membrane is the principal dwelling of several inner nuclear membrane proteins. The inner membrane is connected to a network of intermediate filaments known as nuclear lamina, which is primarily made of lamin. The lamina plays as the site of attachment for chromosomes and serves as a shield for the nucleus.

Both of the inner and outer nuclear membranes are attached to the site of the nuclear pore complexes and the overall structure of the membrane is composed of ribosomes. The nuclear pores control the passages of macromolecules such as RNA and proteins but permit the free passage of ions, water and ATP, as well as other small molecules. This process enables the membrane to exert some control over the information that flows in the cell, due to the fact that macromolecules are the carrier of information in the cell.

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